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Search Results for " diacylglycerol acyltransferase inhibitor-1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T11037 Diacylglycerol acyltransferase inhibitor-1 Others
Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.
T15109 DGAT1-IN-1 Transferase
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
T4681 T863 DGAT-3,DGAT-1 inhibitor Acyltransferase , Transferase
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis...
T16409 OSMI-1 Others , Acyltransferase
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.
T6365 A 922500 A922500,DGAT-1 Inhibitor 4a Acyltransferase , Transferase
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel of anti-targets.
T14375 AZD3988 Transferase
AZD3988 is an orally active and highly potent inhibitor of diacylglycerol acyltransferase-1 (DGAT-1) for the study of diabetes and obesity.
T11827 Pradigastat ANJ908,LCQ908-NXA,LCQ908A,LCQ-908 Transferase
Pradigastat (LCQ-908) is an orally active, potent and selective diacylglycerol acyltransferase 1 (DGAT1) inhibitor for the treatment of constipation, which may be used in the study of obesity and diabetes.
T11016 DGAT-1 inhibitor 2 Transferase
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride s...
T79764 PF-07202954 Acyltransferase
PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against human DGAT2 and effectively reduces liver triglyceride content i...
T75697 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, exhibits IC50 values of 20.1 μM and 34.1 μM, respectively. Additionally, it demonstr...
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